WO2007035363A3 - Compositions and methods for the augmentation and repair of defects in tissue - Google Patents

Compositions and methods for the augmentation and repair of defects in tissue Download PDF

Info

Publication number
WO2007035363A3
WO2007035363A3 PCT/US2006/035676 US2006035676W WO2007035363A3 WO 2007035363 A3 WO2007035363 A3 WO 2007035363A3 US 2006035676 W US2006035676 W US 2006035676W WO 2007035363 A3 WO2007035363 A3 WO 2007035363A3
Authority
WO
WIPO (PCT)
Prior art keywords
compositions
methods
augmentation
repair
defects
Prior art date
Application number
PCT/US2006/035676
Other languages
French (fr)
Other versions
WO2007035363A2 (en
Inventor
Donald A Kleinsek
Adriana Soto
Original Assignee
Dask Technologies Llc
Donald A Kleinsek
Adriana Soto
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dask Technologies Llc, Donald A Kleinsek, Adriana Soto filed Critical Dask Technologies Llc
Priority to EP06814588A priority Critical patent/EP1940424A4/en
Priority to CA002663412A priority patent/CA2663412A1/en
Priority to US11/526,202 priority patent/US20070128174A1/en
Publication of WO2007035363A2 publication Critical patent/WO2007035363A2/en
Publication of WO2007035363A3 publication Critical patent/WO2007035363A3/en
Priority to US12/924,052 priority patent/US20110081323A1/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/33Fibroblasts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Abstract

Compositions and methods of treating a defect in a patient are disclosed, including expanding a culture of autologous cells in vitro to form cultured cells, collecting the cultured cells for introduction into the patient, and depositing the cultured cells with ancillary proteins.
PCT/US2006/035676 2005-09-16 2006-09-14 Compositions and methods for the augmentation and repair of defects in tissue WO2007035363A2 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
EP06814588A EP1940424A4 (en) 2005-09-16 2006-09-14 Compositions and methods for the augmentation and repair of defects in tissue
CA002663412A CA2663412A1 (en) 2005-09-16 2006-09-14 Compositions and methods for the augmentation and repair of defects in tissue
US11/526,202 US20070128174A1 (en) 2005-09-21 2006-09-21 Methods and compositions for organ and tissue functionality
US12/924,052 US20110081323A1 (en) 2005-09-21 2010-09-20 Methods and compositions for organ and tissue functionality

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11/229,237 2005-09-16
US11/229,237 US20070065415A1 (en) 2005-09-16 2005-09-16 Compositions and methods for the augmentation and repair of defects in tissue

Related Child Applications (1)

Application Number Title Priority Date Filing Date
US11/526,202 Continuation-In-Part US20070128174A1 (en) 2005-09-21 2006-09-21 Methods and compositions for organ and tissue functionality

Publications (2)

Publication Number Publication Date
WO2007035363A2 WO2007035363A2 (en) 2007-03-29
WO2007035363A3 true WO2007035363A3 (en) 2009-04-09

Family

ID=37884400

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2006/035676 WO2007035363A2 (en) 2005-09-16 2006-09-14 Compositions and methods for the augmentation and repair of defects in tissue

Country Status (4)

Country Link
US (1) US20070065415A1 (en)
EP (1) EP1940424A4 (en)
CA (1) CA2663412A1 (en)
WO (1) WO2007035363A2 (en)

Families Citing this family (92)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20090074729A2 (en) * 1999-11-05 2009-03-19 Donald Kleinsek Augmentation and repair of spincter defects with cells including fibroblasts
US7799325B2 (en) * 1999-11-05 2010-09-21 Kleinsek Donald A Removal of hypertrophic scars
JP2003517858A (en) * 1999-11-05 2003-06-03 ジェリジーン メディカル コーポレーション Augmentation and repair of age-related soft tissue defects
US20080267923A2 (en) * 1999-11-05 2008-10-30 Donald Kleinsek Hair undifferentiated cells
US20080286242A2 (en) * 1999-11-05 2008-11-20 Donald Kleinsek Augmentation and repair of spincter defects with cells including mesenchymal cells
US20070025958A1 (en) 2000-10-27 2007-02-01 Hadden John W Vaccine immunotherapy
MXPA03003638A (en) 2000-10-27 2004-01-26 Immuno Rx Inc Vaccine immunotherapy for immune suppressed patients.
US20090130066A1 (en) * 2000-11-06 2009-05-21 Gerigene Medical Corporation Augmentation and repair of sphincter defects with cells including muscle cells
US8304238B2 (en) * 2003-03-24 2012-11-06 Nat'l Institute for Environmental Studies Cell culture medium and immobilized preparation of cell adhesion protein or peptide
US8193312B2 (en) 2004-01-28 2012-06-05 The Regents Of The University Of California Bone morphogenic protein binding peptide
WO2005072403A2 (en) 2004-01-28 2005-08-11 The Regents Of The University Of California Bone morphogenic protein binding peptide
US8415302B2 (en) * 2004-01-28 2013-04-09 The Regents Of The University Of California Surgical applications for BMP binding protein
AU2005328325B2 (en) * 2004-11-29 2012-04-05 Department Of Veterans Affairs Activating extraction of demineralized bone matrix
WO2006099137A1 (en) * 2005-03-10 2006-09-21 Uab Research Foundation Endothelial predecessor cell seeded wound healing scaffold
US8778360B2 (en) 2005-10-27 2014-07-15 University Of Notre Dame Extracellular matrix cancer vaccine adjuvant
US8802113B2 (en) 2005-10-27 2014-08-12 University Of Notre Dame Extracellular matrix cancer vaccine adjuvant
WO2007095154A2 (en) * 2006-02-10 2007-08-23 The Brigham And Women's Hospital, Inc. Lectin complement pathway assays and related compositions and methods
US20090318355A1 (en) * 2006-02-15 2009-12-24 Chen Thomas T Compositions and methods for promoting tissue repair and wound healing
US20100105610A1 (en) 2006-07-28 2010-04-29 Children's Memorial Hospital Methods of Inhibiting Tumor Cell Aggressiveness Using the Microenvironment of Human Embryonic Stem Cells
US8106004B2 (en) * 2006-07-28 2012-01-31 Children's Memorial Hospital Methods of inhibiting tumor cell aggressiveness using the microenvironment of human embryonic stem cells
ES2583371T3 (en) 2006-10-11 2016-09-20 The General Hospital Corporation Compositions, methods, and devices to treat liver diseases
US20100093613A1 (en) * 2007-03-09 2010-04-15 Kunkel Eric J Methods for identifying agents and their use for the prevention or stabilization of fibrosis
US20080274543A1 (en) * 2007-05-01 2008-11-06 The Administrators Of The Tulane Educational Fund Neuronal Cell Propagation Using Rotating Wall Vessel
WO2008157060A2 (en) * 2007-06-15 2008-12-24 Ethicon, Inc. Human umbilical tissue-derived cell compositions for the treatment of incontinence
AU2008266311A1 (en) * 2007-06-15 2008-12-24 Ethicon, Inc. Tissue fragment compositions for the treatment of incontinence
EP2173859B1 (en) * 2007-06-29 2016-05-11 Makoto Funaki Soft gel systems in modulating stem cell development
CN106978393A (en) * 2007-06-29 2017-07-25 船木真理 For carrying out mescenchymal stem cell(MSC)The low rigidity gels of growth regulating
CA2695971A1 (en) * 2007-08-15 2009-02-19 Ramot At Tel Aviv University, Ltd. Polypeptides, matrices, hydrogels and methods of using same for tissue regeneration and repair
EP2234642B8 (en) * 2007-11-28 2017-11-01 IRX Therapeutics, Inc. Method of increasing immunological effect
AU2009231849A1 (en) * 2008-03-31 2009-10-08 Lenticular Research Group, Llc Processes and apparatus for preventing, delaying or ameliorating one or more symptoms of presbyopia
CA2749750C (en) * 2008-04-15 2014-01-28 Immanence Integrale Dermo Correction Inc. Skin care compositions and methods of use thereof
WO2009136747A2 (en) 2008-05-07 2009-11-12 한 쎌 주식회사 Cosmetic composition comprising a stem-cell culture fluid, and a production method therefor
CA2724886C (en) 2008-05-23 2017-11-14 Siwa Corporation Methods, compositions and apparatuses for facilitating regeneration
US8609334B2 (en) * 2008-05-29 2013-12-17 The Regents Of The University Of California Biomarkers for painful intervertebral discs and methods of use thereof
US20110189310A1 (en) * 2008-10-08 2011-08-04 Cornell University Small molecule modulators of prongf uptake
WO2010053561A2 (en) * 2008-11-07 2010-05-14 Celdara Medical, Llc Compositions and methods for dendritic cell modulation in post-ischemic wounds
KR101218101B1 (en) * 2009-03-20 2013-01-03 주식회사 스템메디언스 Compositions for Promoting Hair Growth Using Fetus-derived Mesenchymal Stem Cells from Amniotic Fluids
KR101078419B1 (en) * 2009-03-20 2011-10-31 주식회사 스템메디언스 Compositions for Improving Skin Conditions Using Fetus-derived Mesenchymal Stem Cells from Amniotic Fluids
WO2010132867A1 (en) 2009-05-15 2010-11-18 Irx Therapeutics, Inc. Vaccine immunotherapy
US20150335400A1 (en) * 2009-06-17 2015-11-26 The Trustees Of Columbia University In The City Of New York Tooth scaffolds
MX371080B (en) 2009-06-23 2020-01-15 Univ California Enhancement of bmp retention.
KR101108847B1 (en) * 2009-06-30 2012-01-31 재단법인 송도테크노파크 Cosmetic Composition for Wrinkle-Care Comprising Mesenchymal Stem Cell Serum-free Culture Solution
JP5889797B2 (en) 2009-12-08 2016-03-22 アイアールエックス セラピューティクス, インコーポレイテッド Methods to reverse the immunosuppression of Langerhans cells
WO2011119185A1 (en) * 2010-03-26 2011-09-29 La Jolla Institute For Allergy And Immunology Methods of inhibiting inflammation and inflammatory diseases using gal-3bp (btbd17b, lgals3bp, galectin-3 binding protein, mac-2 binding protein)
WO2012013969A1 (en) * 2010-07-26 2012-02-02 The University Of Manchester Targeted differentiation of stem cells
US8435541B2 (en) 2010-09-02 2013-05-07 Bath & Body Works Brand Management, Inc. Topical compositions for inhibiting matrix metalloproteases and providing antioxidative activities
US9649376B2 (en) 2010-09-27 2017-05-16 Siwa Corporation Selective removal of age-modified cells for treatment of atherosclerosis
US20120195969A1 (en) * 2010-09-29 2012-08-02 Aidan Research And Consulting, Llc Treatment of acne by conditioned media
US8721571B2 (en) 2010-11-22 2014-05-13 Siwa Corporation Selective removal of cells having accumulated agents
EP2654793B1 (en) 2010-12-21 2017-09-13 Leidos, Inc. Methods and compositions for wound treatment
WO2012135616A1 (en) * 2011-03-31 2012-10-04 Siwa Corporation Vaccination against advanced glycation end-products
US20140235475A1 (en) 2011-06-27 2014-08-21 Isabelle Carlavan Th17 differentiation markers for acne and uses thereof
US20140221648A1 (en) * 2011-06-27 2014-08-07 Galderma Research & Developement Th17 differentiation markers for acne and uses thereof
WO2013049846A1 (en) * 2011-09-30 2013-04-04 Pawel Kalinski Generation of immunosuppressive myeloid cells using pge2
WO2013071015A1 (en) * 2011-11-11 2013-05-16 The Children's Hospital Of Philadelphia Ex vivo-modified monocytes as local delivery vehicles to treat diseased arteries
CA2869169A1 (en) * 2012-03-30 2013-10-03 University Of Central Florida Research Foundation, Inc. Methods and compositions using fgf-9 to enhance neovascularization and regeneration
US20130330761A1 (en) 2012-06-12 2013-12-12 Celcuity, LLC Whole cell assays and methods
US10149922B1 (en) * 2012-10-24 2018-12-11 The Board Of Trustees Of The Leland Stanford Junior University Engineered collagen matrices for myocardial therapy
US9962428B2 (en) * 2012-12-21 2018-05-08 National University Corporation Nagoya University Composition having tissue-repairing activity, and use therefor
US20140248696A1 (en) * 2013-03-01 2014-09-04 Wisconsin Alumni Research Foundation Methods of maintaining, expanding, and diffrentiating neuronal subtype specific progenitors
US10160950B2 (en) 2013-03-01 2018-12-25 Wisconsin Alumni Research Foundation Methods of maintaining, expanding and differentiating neuronal subtype specific progenitors
EP3003356B1 (en) * 2013-05-31 2019-07-03 Regeneron Pharmaceuticals, Inc. Il-1 antagonists for use in treating alzheimer's disease
WO2015050983A1 (en) 2013-10-01 2015-04-09 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Methods of modulating erythropoiesis with arginine vasopressin receptor 1b molecules
WO2015089380A2 (en) 2013-12-12 2015-06-18 Celcuity Llc Assays and methods for determining the responsiveness of an individual subject to a therapeutic agent
KR20160102069A (en) * 2013-12-27 2016-08-26 텔로리젠, 인크. Compositions and methods for providing active telomerase to cells in vivo
US10533191B2 (en) 2014-01-15 2020-01-14 Serucell Corporation Therapeutic serum obtained from co-cultured cells
TWI625134B (en) * 2014-02-17 2018-06-01 國璽幹細胞應用技術股份有限公司 Mesenchymal stem cell extract and its use
WO2016018761A1 (en) * 2014-07-28 2016-02-04 The Texas A&M University System Mesenchymal stem cells expressing biomarkers that predict the effectiveness of the mesenchymal stem cells for treating diseases and disorders
KR102438295B1 (en) 2014-09-19 2022-08-31 시와 코퍼레이션 Anti-age antibodies for treating inflammation and auto-immune disorders
US10358502B2 (en) 2014-12-18 2019-07-23 Siwa Corporation Product and method for treating sarcopenia
US9993535B2 (en) 2014-12-18 2018-06-12 Siwa Corporation Method and composition for treating sarcopenia
JP6510054B2 (en) 2014-12-31 2019-05-08 ヒュオンス カンパニー リミテッド Composition for ameliorating skin wrinkles comprising an RGD motif containing peptide or fragment thereof
WO2016201424A1 (en) * 2015-06-12 2016-12-15 Thomas Jefferson University Effect of hemopexin therapy after intracerebral hemorrhage
EP3334441B1 (en) * 2015-08-13 2021-06-16 Kamada Ltd. Compositions derived from cohn fraction paste and use thereof
PT3337829T (en) 2016-02-19 2020-02-10 Siwa Corp Method and composition for treating cancer, killing metastatic cancer cells and preventing cancer metastasis using antibody to advanced glycation end products (age)
WO2017222535A1 (en) 2016-06-23 2017-12-28 Siwa Corporation Vaccines for use in treating various diseases and disorders
WO2018081524A1 (en) * 2016-10-28 2018-05-03 Vital Therapies, Inc. Use of conditioned media from extracorporeal blood detoxifying system to supplement organ perfusion solutions
US10995151B1 (en) 2017-01-06 2021-05-04 Siwa Corporation Methods and compositions for treating disease-related cachexia
US10961321B1 (en) 2017-01-06 2021-03-30 Siwa Corporation Methods and compositions for treating pain associated with inflammation
US10858449B1 (en) 2017-01-06 2020-12-08 Siwa Corporation Methods and compositions for treating osteoarthritis
US10925937B1 (en) 2017-01-06 2021-02-23 Siwa Corporation Vaccines for use in treating juvenile disorders associated with inflammation
WO2018175251A1 (en) 2017-03-20 2018-09-27 Celcuity Llc Methods of measuring signaling pathway activity for selection of therapeutic agents
JP2020516648A (en) 2017-04-13 2020-06-11 シワ コーポレーション Humanized monoclonal advanced glycation end product antibody
WO2019005822A1 (en) * 2017-06-28 2019-01-03 The Cleveland Clinic Foundation Treatment of nervous system injury and neurodegenerative disorders and related conditions
KR20200083972A (en) * 2017-09-01 2020-07-09 엑셀 메드, 엘엘씨 Pharmaceutical composition and its use for treating keloid
US11518801B1 (en) 2017-12-22 2022-12-06 Siwa Corporation Methods and compositions for treating diabetes and diabetic complications
US20190224277A1 (en) * 2018-01-22 2019-07-25 CyPhi LLC Bio-mimetic formulation
TWI690332B (en) 2018-09-20 2020-04-11 國立清華大學 Hybrid hydrogel and method of fabricating the same
US20220289804A1 (en) * 2019-06-06 2022-09-15 Aroa Biosurgery Limited Bioactive agents and methods related thereto
CN114533959B (en) * 2022-04-02 2022-12-09 山东隽秀生物科技股份有限公司 Tendon repair material, preparation method and application in preparation of tendon repair product
WO2024011235A1 (en) * 2022-07-08 2024-01-11 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Methods and compositions for improving wound healing
WO2024015794A2 (en) * 2022-07-12 2024-01-18 The Research Institute At Nationwide Children's Hospital Adeno-associated virus gene therapy products and methods

Family Cites Families (74)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3600718A (en) * 1969-12-29 1971-08-24 Dow Corning Inflatable prosthesis
US3665520A (en) * 1970-10-07 1972-05-30 Medical Eng Corp Surgically implantable breast prosthesis
US3911503A (en) * 1974-01-21 1975-10-14 George Hankin Breast prosthesis
US3949073A (en) * 1974-11-18 1976-04-06 The Board Of Trustees Of Leland Stanford Junior University Process for augmenting connective mammalian tissue with in situ polymerizable native collagen solution
US4488911A (en) * 1975-10-22 1984-12-18 Luck Edward E Non-antigenic collagen and articles of manufacture
US4139619A (en) * 1976-05-24 1979-02-13 The Upjohn Company 6-Amino-4-(substituted amino)-1,2-dihydro-1-hydroxy-2-iminopyrimidine, topical compositions and process for hair growth
US4100627A (en) * 1976-05-27 1978-07-18 Dow Corning Corporation Low oiling gel filled flexible articles and gels therefor
US4172298A (en) * 1976-06-16 1979-10-30 Cornelius Rechenberg Breast prosthesis
US4377584A (en) * 1978-04-13 1983-03-22 Merck & Co., Inc. 4-Aza-17β-substituted-5α-androstan-3-one-reductase inhibitors
US4234599A (en) * 1978-10-04 1980-11-18 Scott Eugene J Van Treatment of skin keratoses with α-hydroxy acids and related compounds
US4840628A (en) * 1980-11-21 1989-06-20 Cavon Joseph F Non-enveloped gel prosthesis
US4298998A (en) * 1980-12-08 1981-11-10 Naficy Sadeque S Breast prosthesis with biologically absorbable outer container
FR2499405A1 (en) * 1981-02-10 1982-08-13 Biotherm SLIMMING AND ANTI-CELLULAR COSMETIC COMPOSITION BASED ON A PLANT EXTRACT CONTAINING SAPONINS, AN EXTRACT FROM ARNICA MONTANA L. AND A COLA NUT EXTRACT AND METHOD OF APPLICATION THEREOF
JPS61965Y2 (en) * 1981-02-13 1986-01-14
EP0076158B1 (en) * 1981-09-30 1989-10-25 National Research Development Corporation Compositions comprising encapsulated particles
US4424208A (en) * 1982-01-11 1984-01-03 Collagen Corporation Collagen implant material and method for augmenting soft tissue
AU548341B2 (en) * 1982-02-02 1985-12-05 Unilever Plc Acne treatment composition
US4582640A (en) * 1982-03-08 1986-04-15 Collagen Corporation Injectable cross-linked collagen implant material
FR2524487B1 (en) * 1982-04-05 1985-11-22 Pasteur Institut DNA FRAGMENTS ENCODING POLYPEPTIDES CONTAINING AT LEAST ONE ANTIGENIC DETERMINANT OF PAPILLOMAVIRUS, IN PARTICULAR OF THE HPV 1A TYPE AND CORRESPONDING POLYPEPTIDES
US4760071A (en) * 1984-02-27 1988-07-26 Merck & Co., Inc. 17β-N-monosubstituted carbamoyl-4-aza-5α-androst-1-en-3-ones which are active as testosterone 5α-reductase inhibitors
US4642117A (en) * 1985-03-22 1987-02-10 Collagen Corporation Mechanically sheared collagen implant material and method
GB8604360D0 (en) * 1986-02-21 1986-03-26 Univ Dundee Stimulation of hair growth
US4772284A (en) * 1986-03-27 1988-09-20 Collagenix Corporation Breast prosthesis with improved biocompatibility and method of making the same
US5863531A (en) * 1986-04-18 1999-01-26 Advanced Tissue Sciences, Inc. In vitro preparation of tubular tissue structures by stromal cell culture on a three-dimensional framework
US4803075A (en) * 1986-06-25 1989-02-07 Collagen Corporation Injectable implant composition having improved intrudability
FR2611496B1 (en) * 1987-03-04 1992-07-03 Gueyne Jean COSMETIC ORGANIC SILICIES
GB8708009D0 (en) * 1987-04-03 1987-05-07 Clayton Found Res Injectable soft tissue augmentation materials
US4790848A (en) * 1987-11-27 1988-12-13 Dow Corning Wright Breast prosthesis with multiple lumens
US4969912A (en) * 1988-02-18 1990-11-13 Kelman Charles D Human collagen processing and autoimplant use
US5197983A (en) * 1988-04-19 1993-03-30 W. L. Gore & Associates, Inc. Ligament and tendon prosthesis
FR2639541B1 (en) * 1988-11-29 1993-09-24 Fabre Pierre Cosmetique TOPICAL SLIMMERS CONTAINING CARBOXYL CAFEIN DERIVATIVES NEUTRALIZED BY ORGANIC BASES AND PREPARATIONS USEFUL IN THE TREATMENT OF CELLULITE
US5116605A (en) * 1989-03-09 1992-05-26 Alt John P Composition and skin treatment method therewith for mitigating acne and male-pattern baldness
US5449757A (en) * 1990-06-01 1995-09-12 W. Alton Jones Cell Science Center Mammalian adipogenic factors
US5140200A (en) * 1990-07-17 1992-08-18 General Instrument Corporation Pin diode attenuator
FR2669537B1 (en) * 1990-11-28 1993-02-19 Oreal SLIMMING COMPOSITION BASED ON ALPHA-2-BLOCKERS.
US5192312A (en) * 1991-03-05 1993-03-09 Colorado State University Research Foundation Treated tissue for implantation and methods of treatment and use
JP2774695B2 (en) * 1991-03-29 1998-07-09 コラーゲン コーポレイション Apparatus and method for treating facial wrinkles
US5199942A (en) * 1991-06-07 1993-04-06 Immunex Corporation Method for improving autologous transplantation
CA2071137A1 (en) * 1991-07-10 1993-01-11 Clarence C. Lee Composition and method for revitalizing scar tissue
US5215759A (en) * 1991-10-01 1993-06-01 Chanel, Inc. Cosmetic composition
US5376117A (en) * 1991-10-25 1994-12-27 Corvita Corporation Breast prostheses
US5480644A (en) * 1992-02-28 1996-01-02 Jsf Consultants Ltd. Use of injectable biomaterials for the repair and augmentation of the anal sphincters
US5422261A (en) * 1993-04-16 1995-06-06 Baxter International Inc. Composition containing collagenase and chymopapain for hydrolyzing connective tissue to isolate cells
EP2025353A2 (en) * 1993-04-30 2009-02-18 Massachusetts Institute of Technology Injectable polysaccharide-cell compositions
US5709854A (en) * 1993-04-30 1998-01-20 Massachusetts Institute Of Technology Tissue formation by injecting a cell-polymeric solution that gels in vivo
US5656478A (en) * 1994-02-25 1997-08-12 The Regents Of The University Of California Smooth muscle tissue formation in vivo using cultured smooth muscle cells combined with an extracellular matrix
US5516779A (en) * 1994-06-08 1996-05-14 Merck & Co., Inc. 17β-substituted-6-azasteroid derivatives useful as 5α-reductase inhibitors
US6092528A (en) * 1994-06-24 2000-07-25 Edwards; Stuart D. Method to treat esophageal sphincters
US6044846A (en) * 1994-06-24 2000-04-04 Edwards; Stuart D. Method to treat esophageal sphincters
US5599788A (en) * 1994-07-01 1997-02-04 Advanced Tissue Sciences Method for accelerating skin wound healing with H3 protein
US5516532A (en) * 1994-08-05 1996-05-14 Children's Medical Center Corporation Injectable non-immunogenic cartilage and bone preparation
US20020055786A1 (en) * 1994-08-16 2002-05-09 Anthony Atala Reconstruction of urological structures with polymeric matrices
US5587396A (en) * 1994-08-26 1996-12-24 Mary Kay Inc. Method of ameliorating cellulite by disrupting the barrier function of the stratum corneum
US5510102A (en) * 1995-01-23 1996-04-23 The Regents Of The University Of California Plasma and polymer containing surgical hemostatic adhesives
US5523090A (en) * 1995-02-24 1996-06-04 Chesebrough-Pond's Usa Co., Division Of Conopco, Inc. Skin treatment composition
US5830708A (en) * 1995-06-06 1998-11-03 Advanced Tissue Sciences, Inc. Methods for production of a naturally secreted extracellular matrix
US5591444A (en) * 1995-07-28 1997-01-07 Isolagen Technologies, Inc. Use of autologous dermal fibroblasts for the repair of skin and soft tissue defects
US5888551A (en) * 1995-12-11 1999-03-30 University Of Miami Hair growth stimulating composition
US5842477A (en) * 1996-02-21 1998-12-01 Advanced Tissue Sciences, Inc. Method for repairing cartilage
WO1997041208A1 (en) * 1996-04-26 1997-11-06 Case Western Reserve University Skin regeneration using mesenchymal stem cells
US5759190A (en) * 1996-08-30 1998-06-02 Vts Holdings Limited Method and kit for autologous transplantation
US6325798B1 (en) * 1998-02-19 2001-12-04 Curon Medical, Inc. Vacuum-assisted systems and methods for treating sphincters and adjoining tissue regions
JP4441115B2 (en) * 1998-03-13 2010-03-31 オシリス セラピューティクス,インコーポレイテッド Methods and uses of human non-self mesenchymal stem cells
US6866842B1 (en) * 1998-05-01 2005-03-15 University Of Pittsburgh Muscle-derived cells (MDCs) for treating muscle-or bone-related injury or dysfunction
US6835377B2 (en) * 1998-05-13 2004-12-28 Osiris Therapeutics, Inc. Osteoarthritis cartilage regeneration
US6432710B1 (en) * 1998-05-22 2002-08-13 Isolagen Technologies, Inc. Compositions for regenerating tissue that has deteriorated, and methods for using such compositions
US6802841B2 (en) * 1998-06-04 2004-10-12 Curon Medical, Inc. Systems and methods for applying a selected treatment agent into contact with tissue to treat sphincter dysfunction
US6156032A (en) * 1998-09-30 2000-12-05 Scimed Life Systems, Inc. Method for causing a stricture of a body passageway
WO2000073418A2 (en) * 1999-05-28 2000-12-07 Pacgen Technologies Llc A method of using autologous fibroblasts to promote healing of wounds and fistulas
JP2003517858A (en) * 1999-11-05 2003-06-03 ジェリジーン メディカル コーポレーション Augmentation and repair of age-related soft tissue defects
WO2001078754A2 (en) * 2000-04-14 2001-10-25 University Of Pittsburgh Soft tissue and bone augmentation and bulking utilizing muscle-derived progenitor cells, compositions and treatments thereof
JP2005511207A (en) * 2001-12-10 2005-04-28 コルバー・ライフサイエンス・リミテッド Intervertebral disc treatment methods, devices, and preparations
US7326571B2 (en) * 2003-07-17 2008-02-05 Boston Scientific Scimed, Inc. Decellularized bone marrow extracellular matrix
US7375077B2 (en) * 2003-09-19 2008-05-20 The Board Of Trustees Of The University Of Illinois In vivo synthesis of connective tissues

Non-Patent Citations (6)

* Cited by examiner, † Cited by third party
Title
COOL ET AL.: "The osteoblast-heparan sulfate axis: Control of the bone cell lineage.", INT. JOUR. BIOCHEMISTRY & CELL BIOLOGY, vol. 37, no. 9, September 2005 (2005-09-01), pages 1739 - 1745, XP003021961 *
GRIESE ET AL.: "Isolation and Transplantation of Autologous Circulating Endothelial Cells Into Denuded Vessels and Prosthetic Grafts Implications for Cell-Based Vascular Therapy.", CIRCULATION., vol. 108, no. 21, 25 November 2003 (2003-11-25), pages 2710 - 2715, XP003021959 *
HUARD ET AL.: "Transplantation of dermal fibroblasts expressing MyoD1 in mouse muscles.", BIOCHEM BIOPHYS RES COMMUN., vol. 248, no. 3, 30 July 1998 (1998-07-30), pages 648 - 654, XP003021963 *
PATRICK.: "Tissue Engineering Strategies for Adipose Tissue Repair.", ANAT. RECORD, vol. 263, no. 4, 1 August 2001 (2001-08-01), pages 361 - 366, XP003021962 *
REYES ET AL.: "Purification and ex vivo expansion of postnatal human marrow mesodermal progenitor cells.", BLOOD, vol. 98, no. 9, 1 November 2001 (2001-11-01), pages 2615 - 2625, XP003021960 *
SHAMBLOTT ET AL.: "Human embryonic germ cell derivatives express a broad range of developmentally distinct markers and proliferate extensively in vitro.", PROC. NAT. ACAD. SCI., vol. 98, no. 1, 2 January 2001 (2001-01-02), pages 113 - 118, XP002939895 *

Also Published As

Publication number Publication date
US20070065415A1 (en) 2007-03-22
EP1940424A2 (en) 2008-07-09
EP1940424A4 (en) 2011-04-20
CA2663412A1 (en) 2007-03-29
WO2007035363A2 (en) 2007-03-29

Similar Documents

Publication Publication Date Title
WO2007035363A3 (en) Compositions and methods for the augmentation and repair of defects in tissue
EP2420567A3 (en) Methods and compositions for treatment of bone defects with placental cell populations
MX2009014273A (en) Methods and compositions for optimized expansion and implantation of mesenchymal stem cells.
WO2007035843A3 (en) Methods and compositions for organ and tissue functionality
AU2005221582A8 (en) Tissue repair with multipotent cells
WO2007147014A3 (en) Method and systems for using biopolymer-based beads and hydrogels
WO2012002986A3 (en) Decellularized and delipidized extracellular matrix and methods of use
WO2010039823A8 (en) Compositions and methods for tissue repair with extracellular matrices
EP2048227A3 (en) Methods for proliferating stem cells
WO2007080590A3 (en) Human embryonic stem cell-derived connective tissue progenitors for tissue engineering
EP2471904A3 (en) Placental stem cell populations
EP1961823A4 (en) Fermentation and culture method, fermented plant extract, composition containing fermented plant extract, method for producing lipopolysaccharide and lipopolysaccharide
WO2006050330A3 (en) Platelets from stem cells
MX2012000455A (en) Conditioned medium and extracellular matrix compositions from cells cultured under hypoxic conditions.
GB2443938B (en) Preparation of tissue for meniscal implantation
SG178914A1 (en) Stem cell conditioned medium compositions
EP2172231A4 (en) Tissue engineering tendon and construction methods in vitro thereof
MX2012005782A (en) Lyophilization methods, compositions, and kits.
WO2010062911A3 (en) Compositions and methods of functionally enhanced in vitro cell culture system
WO2007103379A3 (en) Method for endothelial cell extraction from adipose tissues
WO2006017176A3 (en) Scaffoldless constructs for tissue engineering of articular cartilage
WO2011105821A3 (en) Serum-free stem cell culture composition, tissue regeneration composition containing same, and tissue regeneration method using same
WO2008081818A1 (en) Material for ameliorating skin tissue and method for producing the same
EP2341147A3 (en) Preprimitive streak and mesendoderm cells
MX336067B (en) Stem cell for therapeutic use which is derived from human monocyte, and method for inducing same.

Legal Events

Date Code Title Description
DPE2 Request for preliminary examination filed before expiration of 19th month from priority date (pct application filed from 20040101)
121 Ep: the epo has been informed by wipo that ep was designated in this application
NENP Non-entry into the national phase

Ref country code: DE

WWE Wipo information: entry into national phase

Ref document number: 2006814588

Country of ref document: EP

ENP Entry into the national phase

Ref document number: 2663412

Country of ref document: CA

DPE2 Request for preliminary examination filed before expiration of 19th month from priority date (pct application filed from 20040101)